Longevity Biomarker Tracking Protocol
What gets measured gets managed. This protocol outlines the key biomarkers to track for longevity, optimal testing frequencies, and target ranges. It covers daily wearable metrics, quarterly blood work, and annual imaging for comprehensive healthspan monitoring.
Expected Outcome
Early detection and intervention capability
How to Do It
Daily wearable tracking
Track sleep (stages, HRV), resting heart rate, and activity with Oura, Whoop, or Apple Watch.
DailyWeekly body composition
Track weight, body fat %, and muscle mass with smart scale. Look for trends, not daily fluctuations.
WeeklyQuarterly comprehensive blood panel
Include: Lipids, fasting glucose, HbA1c, liver enzymes, kidney function, thyroid, inflammatory markers (hsCRP), vitamin D.
Every 3 monthsBi-annual advanced longevity markers
Test: Apolipoprotein B, Lp(a), homocysteine, omega-3 index, NAD+ levels, hormones panel.
Every 6 monthsAnnual DEXA scan
Measure bone density, body composition (muscle vs fat distribution), and visceral fat precisely.
YearlyPeriodic full-body MRI
Services like Prenuvo provide comprehensive imaging for early cancer detection and organ assessment.
Every 1-3 years based on riskResearch Evidence
This protocol is based on 1 peer-reviewed study. Click any link to verify the research on PubMed.
Biomarkers of Aging and Longevity
Levine ME, et al. • Aging Cell (2018)
Key Finding: Multi-system biomarker panels predict biological age and mortality risk better than any single marker.
Implementation Tools & Resources
Interactive Tools
Safety Notes & Contraindications
- •Some tests require fasting - follow preparation instructions
- •MRI contraindicated with certain implants
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